Effect of Micellization pH on Properties of Sphere-like Mesoporous Hydroxyappatite


1 National Cell Bank of Iran, Pasteur Institute of Iran

2 School of Pharmacy, Shahid Beheshti University of Medical Sciences

3 Materials Engineering, Iran University of Science and Technology (IUST)


Mesoporous hydroxyapatites were syntesized by self-assembly method using Cetyltrimethylammonium bromide (CTAB) as cationic surfactant and 1-dodecanethiol as pore expander with pore expander/surfactant mass ratio of 4.22 and synthesis temperature of 80 °C in different micellization pH. The field emission-scanning electron microscopy (FESEM), x-ray diffraction (XRD), Brunauer-Emmett-Teller (BET) surface area analysis, pore size distribution plot (Barrettt, Joyner, and Halenda (BJH) method), fourier transform infrared spectroscopy (FTIR) and Low-angle x-ray diffraction (LA-XRD) results beside the titration investigation of 1-dodecanethiol revealed that ionizied 1-dodecanethiol concentration ([RS-]) is increased exponentially by changes in pH. The micellization pH has a key role in Physico-chemical characteristics of samples. Increase in pH can change the ionization degree of 1-didecanethiol and swelled the micelle and also led to larger pores (pore diameter of 2.93 in lower pH and 24.48 in higher pH). Changes in the micellization pH also effect on the dielectric constant of water and led to variation in patricle size.