@article { author = {Clausen, E. C. and Basu, R. and Najafpour, Ghasem}, title = {Bioreactor Scale-up for Water-Gas Shift Reaction}, journal = {International Journal of Engineering}, volume = {9}, number = {3}, pages = {121-129}, year = {1996}, publisher = {Materials and Energy Research Center}, issn = {1025-2495}, eissn = {1735-9244}, doi = {}, abstract = {A scale-up study has been performed with three different size reactors to establish the optimum operating conditions for the hydrogen production from synthesis gas by biological water-gas shift reaction using the photosynthetic bacterium Rhodosprilliunt rubrum. Optimum medium composition and operating conditions previously determined in a bench scale 1.25 L continuous stirred tank reactor (CSTR) were used for this study with geometrically similar 2.5, 5.0 and 14.0 L CSTR. The hydrogen production rate, cell concentration and carbon monoxide (CO) conversion were monitored in this scale-up study. The light energy supply was linearly increased with the working volume of the reactors. The agitation rates were determined by the equal power/volume rule. There were good agreement between the calculated agitation rates and the experimentally observed values for all the three different reactors, A 70% carbon monoxide conversion was obtained with 30, 60 and 150 sccm gas flow rate for the 2.5, 5.0 and 14.0 L fermentors respectively. At 70% CO conversion the 2.5 and 5.0 L reactors showed 25% improvement ir~ performance and the 14.0 L reactor showed 11% improvement. The estimated mass transfer coefficients for all four reactors showed very similar values under the optimum operating condition (average KLa= 117 h-1). A 664 h long performance of the process show very stable behavior.}, keywords = {Bioreactor Scale,up,Water,gas Shift,Hydrogen production,Rhodospirilliun Rubrum. Photosynthetic Bacterium}, url = {https://www.ije.ir/article_71153.html}, eprint = {https://www.ije.ir/article_71153_e3fd84e1fba21b9a1cba2eef0b127c06.pdf} }